Microdose Calculator
Use this planner to estimate a low-dose amount based on a known reference dose and your chosen protocol cadence.
What this microdose calculator is for
This calculator gives you a simple estimate for microdosing plans using three core inputs: a reference full dose, a microdose percentage, and a dosing schedule. Instead of guessing, you can quickly see an estimated amount per dosing day and a total amount for your plan window.
It is designed as an educational planning tool, not a medical recommendation. Everyone responds differently to compounds, supplements, and botanicals. If you are considering any protocol that may affect mood, cognition, blood pressure, sleep, or medication interactions, speak with a licensed clinician first.
How the calculation works
1) Per-dose estimate
The core formula is straightforward:
- Microdose amount = Reference dose × (Percentage ÷ 100)
Example: if your reference dose is 200 mg and you choose 10%, your estimated microdose is 20 mg.
2) Number of dosing days
The calculator then counts dose days based on your selected cadence and total plan length in weeks. Different protocols lead to very different totals over time.
- Fadiman: 1 day on, 2 off (repeating)
- Stamets-style cadence: 4 days on, 3 off (repeating)
- Every other day: alternates on/off
- Daily: every day in the plan window
3) Total amount needed
- Total planned amount = Microdose amount × Number of dosing days
If you enter capsule size, the calculator also estimates approximate capsules per dose and total capsules needed.
Why schedule matters
Many people focus only on per-dose amount, but consistency and spacing can affect outcomes as much as dose size. A lower dose used too frequently may still become excessive for some individuals. Conversely, a conservative schedule with clear rest days can make it easier to observe effects and adjust responsibly.
Track sleep quality, focus, mood stability, appetite, and anxiety. If side effects increase, reducing dose or increasing off-days is often safer than pushing through.
Practical tips for responsible use
- Start at the low end of your intended range and increase only if needed.
- Keep one variable constant at a time (dose, then schedule).
- Use a reliable scale and consistent units.
- Avoid stacking multiple new compounds at once.
- Pause immediately if adverse effects appear.
- Review local laws and regulations in your area.
Important safety notes
This page does not provide medical, legal, or psychiatric advice. Certain substances can be unsafe or illegal, and interactions with antidepressants, stimulants, blood pressure medications, or other prescriptions can be significant. If you have a history of bipolar disorder, psychosis, panic disorder, cardiovascular disease, or seizure risk, consult a healthcare professional before attempting any self-directed dosing protocol.