Calculate Your Phenotypic Age (PhenoAge)
Enter your recent lab values to estimate biological age using the Levine PhenoAge model.
What is PhenoAge?
PhenoAge (phenotypic age) is a biomarker-based estimate of biological aging. Instead of using only your birthdate, it combines chronological age with blood markers linked to inflammation, metabolic function, liver function, kidney function, and blood cell characteristics.
The basic idea is simple: two people can both be 45 years old, but one may have biomarker patterns that look “younger” or “older” biologically. PhenoAge helps quantify that difference in a single number.
Biomarkers used in this calculator
- Albumin – linked to nutrition, inflammation, and overall resilience.
- Creatinine – a marker related to kidney function.
- Glucose – reflects glycemic status and metabolic health.
- C-reactive protein (CRP) – a marker of systemic inflammation.
- Lymphocyte percentage – reflects immune profile.
- MCV – average red blood cell size.
- RDW – variation in red blood cell size, often associated with stress and inflammation.
- Alkaline phosphatase (ALP) – associated with liver/bone biology and overall health risk.
- WBC count – broad immune and inflammatory signal.
How to interpret your result
1) Estimated PhenoAge
This is your calculated biological age based on the model. If your PhenoAge is lower than your chronological age, your biomarker profile appears biologically younger in this framework.
2) Age acceleration (PhenoAge − chronological age)
A negative value suggests “slower” biological aging relative to your calendar age. A positive value suggests “faster” biological aging. Small differences are common and can vary with hydration, acute illness, sleep, stress, and lab timing.
3) Estimated 10-year mortality score
The calculator also displays a model-based mortality estimate used internally by the PhenoAge equation. Think of this as a statistical risk signal, not a personal prediction of what will happen to you.
Tips for getting a more useful reading
- Use fasting labs when possible and avoid testing during acute infections.
- Use values from the same lab panel/date to reduce measurement drift.
- Retest over time (for example every 3–6 months) instead of focusing on one snapshot.
- Track trends alongside blood pressure, body composition, fitness, sleep, and lifestyle habits.
Can you improve PhenoAge?
In many people, risk-related biomarkers improve with consistent fundamentals:
- Regular aerobic + resistance exercise
- High-quality sleep and stable sleep schedule
- Nutrition emphasizing fiber, protein adequacy, and minimally processed foods
- Body fat reduction when overweight
- Blood sugar and blood pressure management
- Smoking cessation and moderation of alcohol intake
- Diagnosis and treatment of underlying medical conditions
Important limitations
PhenoAge is a population-derived model, not a complete measure of your healthspan or longevity. It cannot account for every factor that matters, such as genetics, medication effects, training status, imaging findings, functional capacity, or life circumstances. Use it as one useful signal among many.