Rekovelle Daily Dose Estimator
Enter anti-Müllerian hormone (AMH) and body weight to estimate a daily follitropin delta (Rekovelle) dose using a transparent educational model.
Model details: AMH < 15 pmol/L uses fixed 12 mcg/day; AMH 15–40 pmol/L linearly scales 0.19→0.10 mcg/kg; AMH ≥ 40 pmol/L uses 0.10 mcg/kg; then constrained to 6–12 mcg/day and rounded to nearest 0.33 mcg.
What this Rekovelle dose calculator does
This page provides a practical way to estimate a starting daily dose for Rekovelle (follitropin delta) in controlled ovarian stimulation for IVF/ICSI cycles. The estimator uses two key inputs commonly used in individualized stimulation protocols:
- AMH (anti-Müllerian hormone) as a marker of expected ovarian response
- Body weight to scale the dose when AMH is in the intermediate-to-higher range
The goal is not self-medication. The goal is to help patients and clinicians communicate clearly about dose rationale before and during treatment.
Why AMH and body weight matter for dosing
Reproductive response to FSH varies a lot between patients. Some patients are poor responders and may need stronger stimulation, while others can over-respond and face a higher risk of ovarian hyperstimulation syndrome (OHSS). AMH helps estimate this response tendency in advance.
Body weight also changes drug exposure and ovarian response. In individualized strategies, combining AMH + weight can reduce extremes of under- or over-stimulation compared with one-size-fits-all approaches.
Estimation logic used in this tool
1) AMH below 15 pmol/L
A fixed estimate of 12 mcg/day is used. This reflects a higher stimulation starting point often considered when ovarian reserve is lower.
2) AMH between 15 and 40 pmol/L
The tool applies a linear AMH-based factor from 0.19 mcg/kg down to 0.10 mcg/kg. The factor is multiplied by body weight to estimate daily dose.
3) AMH at or above 40 pmol/L
The estimator uses 0.10 mcg/kg/day, then applies safety bounds.
4) Guardrails and pen rounding
- Dose is constrained to 6 to 12 mcg/day
- Final value is rounded to the nearest 0.33 mcg (typical dosing increment)
How to use your result in real life
- Use a recent AMH result from a reliable laboratory.
- Confirm AMH units before entering data (ng/mL vs pmol/L).
- Bring the estimated dose to your fertility appointment.
- Discuss protocol type (antagonist/agonist), trigger plan, and OHSS risk profile.
- Expect adjustments based on follicular growth and hormone monitoring.
Important clinical caveats
Even excellent calculators cannot replace individualized clinical judgement. Real treatment decisions also depend on age, antral follicle count, prior cycle outcomes, PCOS status, estradiol trends, ultrasound findings, and clinic-specific protocols.
- Do not start, stop, or change gonadotropin doses without specialist direction.
- Do not use this as emergency advice.
- If symptoms suggest OHSS (pain, bloating, rapid weight gain, shortness of breath), contact your care team immediately.
FAQ
Can I use AMH in ng/mL?
Yes. This tool converts ng/mL to pmol/L automatically using 1 ng/mL ≈ 7.14 pmol/L.
Is this an official prescribing calculator?
No. It is an educational estimator designed for conversation and planning support.
Does this calculator guarantee egg yield or pregnancy?
No. Stimulation response and IVF outcomes vary for many reasons beyond starting dose.
Bottom line
A Rekovelle dose calculator can make protocol discussions clearer by translating AMH and body weight into a structured starting estimate. Use it to ask better questions and to understand your care plan—but keep final decisions with your fertility specialist.